Fig. 4
Effect of KGS-NE treatment on Vero E6 cells infected by human coronavirus OC43 (HCoV-OC43). A, B Cell viability in Vero E6 cells treated with KGS-NE, including the determination of IC50 value. C RNA levels in HCoV-OC43-infected Vero E6 cells treated with KGS-NE. D Visualization of up-and down-regulated Differential Gene Expressions (DEGs) using a volcano plot. E Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis indicating significant signaling pathways. F Heatmap representation of DEGs involved in the ABC transporters signaling pathway. G Gene Ontology (GO) analysis of biological processes (BP), cellular component (CC), and molecular interactions (MF)